2. Signaling Pathways
  3. GPCR/G Protein
    Neuronal Signaling
  4. 5-HT Receptor
  5. 5-HT Receptor Ligand

5-HT Receptor Ligand

5-HT Receptor Isoform Comparison

5-HT Receptor Ligands (5):

Cat. No. Product Name Effect Purity
  • HY-W741575
    Iloperidone carboxylic acid
    		Ligand
    Iloperidone carboxylic acid (P95-12113) is the metabolite of Iloperidone (HY-17410). Iloperidone carboxylic acid exhibits good affinity for 5-HT2A receptor with pKi of 8.15, and moderate affinity for adrenergic receptor α1/α2B/α2C.
  • HY-170474
    2-Methyl-N,N-dimethyltryptamine
    		Ligand
    2-Methyl-N,N-dimethyltryptamine (2,N,N-TMT, compound 15) has binding affinity for serotonin (5-HT) receptor, with the pA2 of 6.04. 2-Methyl-N,N-dimethyltryptamine plays an important role in neurological disease research.
  • HY-168747
    4-Bromo-2,5-DMMA
    		Ligand
    4-Bromo-2,5-DMMA (Compound 2) has affinity for 5-HT2 binding sites. 4-Bromo-2,5-DMMA has an ED50 of 0.82 mg/kg in the rat discrimination tests.
  • HY-156239
    Dopamine D3 receptor ligand-5
    		Ligand
    Dopamine D3 receptor ligand-5 (13a), a Cariprazine (HY-14763) analogue, is a dopamine D3 receptor ligand, with Ki values of 2.85 nM and 0.14 nM for D2R and D3R, respectively.
  • HY-169440
    6-Fluoro-N,N-diethyltryptamine
    		Ligand
    6-Fluoro-N,N-diethyltryptamine (6-F-DET) has affinity for 5-HT2A receptors.